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Aesthetic Medicine

What is Botox? Get the basics on this toxin

published on 28.08.2025 by Dr. Djian
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Summary
  • BOTOX IN BRIEF: DEFINITION, ORIGIN AND BIOLOGICAL FUNCTION
  • WHEN IS BOTOX USED TODAY?
  • HOW IS A BOTOX INJECTION PERFORMED?
  • RISKS AND SIDE EFFECTS OF BOTOX
  • WHAT YOU NEED TO KNOW ABOUT USING BOTOX
In short
  • Origin and safety from bacteria Clostridium botulinum, Once purified and dosed, this powerful poison becomes a safe and controlled medicine.
  • Targeted mechanism It blocks nerve transmission at the neuromuscular junction, causing reversible, localized relaxation.
  • Multiple applications used in aesthetics to smooth expression areas (forehead, eyebrows, crow's feet), nose wrinkles) and in medicine to treat migraines, hyperhidrosis, bruxism and dystonia.
  • Essential precautions These include prior consultation, known contraindications (pregnancy, breast-feeding, neuromuscular diseases), and the need for a qualified practitioner.
  • Temporary results visible improvement in just a few days, lasting an average of 4 to 6 months, with a natural look if the procedure is well performed.

Every wrinkle tells a story. But some don't look like you anymore.

Botox can precisely reduce muscle contractions the cause of facial wrinkles: forehead, eyebrow, eyelid, crow's feet. A light, well-dosed injection, performed by an aesthetic doctor, and your skin looks more rested, your features more harmonious, without ever freezing your smile.

From a botulinum toxin produced by a bacterium, this molecule, known to cause botulism, is now a recognized treatment in France. aesthetic medicine and therapeutic. It acts by blocking the protein involved in nerve signal transmission, inducing targeted, temporary muscle relaxation.

In just a few days, results become visible and last for several months. There are no known contraindications, and side effects are rare. And with a good practitioner, the risk of asymmetry or complications is virtually nil.
Still wondering about Botox? Find out here what you don't always hear in the office.

 

BOTOX IN BRIEF: DEFINITION, ORIGIN AND BIOLOGICAL FUNCTION

 

CLOSTRIDIUM BOTULINUM: WHEN NATURE CREATES A MEDICINE

 

Behind the name Botox lies botulinum toxin type A, a natural 100% product produced by bacteria Clostridium botulinum. The same bacteria responsible for food botulism? Exactly! But rest assured: purified, dosed and controlled, this toxin becomes a precision medicine.

A fascinating technical detail: this molecule degrades under the effect of heat, but resists perfectly in an acidic environment. This is why laboratories can store and stabilize it for safe medical use.

 

THE EVOLUTION OF BOTOX: FROM THE MILITARY LABORATORY TO YOUR FROWN LINES

 

Infographic on the history of Botulinum Toxin

 

The history of Botox is like a scientific thriller! Discovered in the 1940s, this toxin was initially of interest to the military as a biological weapon potential. Fortunately, science has gone in a completely different direction.

In the 1970s, doctors discovered its therapeutic potential to treat muscle spasms. It wasn't until the 1990s that aesthetic use revolutionized the world of anti-ageing medicine. The present day, more than 7 million injections are performed every year worldwide according to a study published on ISAPS.

 

THE ACTION MECHANISM: A TEMPORARY, TARGETED INTERRUPTION

 

infographic Botox effect on muscle

 

Here's how Botox works its «scientific magic»: it attacks directly the neuromuscular junction, the meeting point between your nerve and your muscle.

Toxin blocks acetylcholine release, a neurotransmitter essential for muscle contraction. The result? The muscle relaxes completely for several months, without affecting the sensitivity of your skin.

This flaccid paralysis is totally reversible: your body naturally builds new nerve endings, and the effect gradually fades. This is why touch-ups are required every 4 to 6 months.

 

WHEN IS BOTOX USED TODAY?

 

INDICATIONS IN AESTHETIC MEDICINE: WRINKLES AND FACIAL EXPRESSION

 

Contrary to popular belief, Botox doesn't turn you into a statue! This botulinum or botulinum toxin targets with surgical precision the areas where your lion wrinkles, forehead wrinkles and crow's feet appear.

Thetoxin action ? It temporarily blocks the’nerve impulse to the overactive muscles responsible for those unsightly creases. Just a few minutes at your doctor's, and the excessive movement that creases your features naturally subsides.

The result will surprise you: a natural, relaxed appearance, never static. Your eyes regain their radiance, your general appearance gains in freshness. It's the’toxin aesthetics at its best: smoothing without masking, relaxing without paralyzing.

 

MEDICAL INDICATIONS: DISEASES AND FUNCTIONAL DISORDERS

 

Aesthetics aside, this toxin molecule reveals impressive therapeutic properties! Visit botulinum toxin injections are used to treat a whole range of pathologies:

  • Hyperhidrosis Toxin: that excessive perspiration that spoils your day? The toxin paralyzes the cells responsible for excessive sweating. A small, life-changing intervention!
  • Bruxism The nocturnal grinding that destroys your teeth sometimes calls for this therapy. The toxin relaxes overactive chewing muscles.
  • Dystonia spasmodic torticollis, blepharospasm... These involuntary movements are calmed by the targeted action of the toxin type A.
  • Chronic migraine a field where results are astonishing! Regular injections reduce the frequency and intensity of attacks.

Each pathology requires a specific approach, certain contraindications exist depending on your general condition. Your doctor will assess whether this part of medicine can help you, taking into account the costs and frequency of sessions required for these treatments.

The advantage? The procedure is painless, and the effects are limited in time, offering valuable respite from these functional problems.

 

HOW IS A BOTOX INJECTION PERFORMED?

 

PRECAUTIONS AND CONTRAINDICATIONS

 

All botox injection begins with a thorough consultation in an ophthalmology practice or with an ophthalmologist. qualified aesthetic physician. This preliminary appointment enables us to assess your overall medical load and history, and to detect any risk situations.

The main contraindications? Pregnancy, breastfeeding, active local infections or neuromuscular disorders pre-existing conditions. Your practitioner will also check whether you are taking any anticoagulants.

This step is never optional: it guarantees your safety and the natural expression of your nerve cells after the treatment.

 

PROCEEDINGS OF THE SESSION

 

The big day has arrived!
The intervention takes place directly at the, without hospitalization. Your specialist uses a micro-needle to precisely target areas of the upper face for action.

Allow 5 to 10 minutes, depending on the area to be covered. How does it feel? A few mild tingling, sometimes a small local hematoma which quickly disappears.

The advantage of this approach therapeutic or cosmetic ? You can resume your activities immediately, with just a few simple instructions to follow.

 

EFFECTS AND DURATION OF TREATMENT

 

Be patient! First signs of improvement between day 3ᵉ and day 10ᵉ. This period corresponds to the time required for the botulinum toxin completely blocks the release of’acetylcholine at the neuromuscular junctions.

A relaxed appearance usually lasts 4 to 6 months, depending on your personal metabolism and the activity of your frontal muscle. Contrary to popular belief, this period can even be extended with regular sessions!

Why this variability? Each organism reacts differently according to its age, lifestyle and the emotional load it is subjected to on a daily basis.

 

BOTOX AND IMMUNOLOGY: WHY SOME PEOPLE BECOME RESISTANT TO THE TOXIN OVER TIME

 

Here's a fascinating phenomenon that few are aware of: the formation of neutralizing antibodies. Some organisms develop a« immunological memory »against botulinum toxin.

How does it work? With repeated sessions, your immune system can modify its response and produce specific defenses. The result: partial or total loss of effectiveness of the treatment.

Aggravating factors? Overdose, injections too close together or use of products of dubious quality. Fortunately, this phenomenon remains exceptional in aesthetic medicine, unlike certain neurological pathologies where it is better documented.

By adhering to the recommended intervals and choosing an experienced practitioner, you can drastically minimize this risk. And if this happens to you, there are always alternatives to restore the desired natural expression.

 

RISKS AND SIDE EFFECTS OF BOTOX

 

POSSIBLE SIDE EFFECTS

 

In a controlled medical setting, complications are exceptional! The most frequently observed effects include drooping eyelids (ptosis), slight asymmetry, or temporary headaches.

Although rare, these inconveniences are generally due to imprecise technique or inappropriate dosage. The good news? They disappear naturally within a few weeks, as the toxin wears off.

But beware: these minor side effects have nothing to do with the dramatic complications observed in illegal contexts!

 

IMPORTANCE OF THE PROFESSIONAL

 

Here's why choosing the right practitioner is crucial! L‘he ANSM reminds us that botulinum toxin injections are reserved for authorized healthcare professionals. Specialists in plastic, reconstructive and aesthetic surgery, dermatology, face and neck surgery, maxillofacial surgery and ophthalmology.

These healthcare professionals master facial anatomy, know the precise dosages for each muscle and respect safety protocols. They only use certified products, purchased through official channels.

A recent alert from ANSM (Agence nationale de sécurité du médicament) dramatically confirms this: between August and September 2024, eight serious pharmacovigilance cases linked to illegal injections of botulinum toxin have been reported. These patients developed severe botulism, with difficulty speaking or swallowing (false routes), difficulty walking, blurred or double vision, and breathing difficulties, requiring hospitalization in intensive care.

Unfortunately, illegal botulinum toxin injections are on the increase, often promoted on social networks by non-doctors.

Your safety is worth much more than a few euros saved! Always choose a licensed medical practice, check your practitioner's qualifications, and avoid overly tempting offers on the internet or social networks.

For secure, personalized treatment, make an appointment with the Docteur Djian, certified in aesthetic medicine.

 

WHAT YOU NEED TO KNOW ABOUT USING BOTOX

 

Botox, considered one of the most powerful poisons, has become a safe, controlled treatment in expert hands. Used in low doses, it relaxes certain areas of the face in a targeted manner, for a natural look. While it does not alter features or halt aging, it does attenuate visible signs, leaving the face smoother, rested and harmonized. Its temporary effects vary according to skin type, age, area treated and, above all, the practitioner's expertise.

Looking for a fresh, harmonious face? Make an appointment today with Docteur Djian and discover all the benefits of Botox..

 

Sources

Your Questions

FREQUENTLY ASKED QUESTIONS ABOUT BOTULINUM TOXIN

HYALURONIC ACID OR BOTOX?

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The confusion arises from the fact that these two methods are often proposed to rejuvenate the face, but their logic is totally different. One blocks the transmission that causes targeted paralysis, while the other fills in lost volume with a moisturizing gel. In practice, they may be complementary, but they are not based on the same protein or the same method. To better understand the difference, read our dedicated article : What's the difference between botulinum toxin and hyaluronic acid?

HOW MUCH DOES BOTOX COST?

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Prices generally start at around 250 euros and can exceed 500 euros when treating several zones at the same time. The price of Botox injections varies according to the area concerned, the quantity injected and the specialist performing the procedure. Each center sets its fees according to its expertise, the time spent and the certified products used. It's advisable to ask for a precise estimate during the initial consultation, as costs can also vary depending on the city, the reputation of the dermatologist and the complexity expected.

Dr. Djian charges a fixed price of 400 euros incl. VAT (including touch-ups) to treat forehead wrinkles, frown lines and crow's feet in a single session.

CAN BOTOX BE COMBINED WITH HYALURONIC ACID?

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Yes, both approaches are often complementary. The toxin limits excessive contraction of the muscles responsible for wrinkles, while hyaluronic acid restores missing volumes. Combining the two techniques in the same treatment plan optimizes facial harmonization: smoothing without stiffening, and restoring curves.

However, each combination must be considered on a case-by-case basis, with a personalized plan drawn up by an experienced dermatologist to avoid any undesirable interactions.

WHAT IS BABY BOTOX

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The “Baby Botox”corresponds to micro-dose injections in specific areas to prevent the appearance of fine lines. This gentle method doesn't seek to transform, but to preserve the freshness of a look or a smile. The gradual, subtle approach is particularly appealing to young customers.

WHY CONTRACT FACIAL MUSCLES AFTER BOTOX INJECTIONS

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Contraction of certain facial groups for 3 to 4 days after the injections promotes targeted diffusion of the molecule into the targeted areas, by saturating the receptors at the junction between the nerve and the targeted tissue. These brief contractions (a few seconds, 3 to 4 times a day) optimize molecule fixation, making the result more homogeneous and long-lasting.

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Dr. Jérémy Djian
Dr. Jérémy Djian

Dr Jérémy Djian is a plastic surgeon based at 5 square Thiers, near the Victor Hugo roundabout, in the 16th arrondissement of Paris.

He trained in Paris and remains attached to the hospital in the prestigious department of Pr Laurent Lantieri.

 

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