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Dr Jérémy Djian, 5 Square Thiers , 75016
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Aesthetic Medicine

Hyaluronic acid duration and efficacy of injections over time

published on 27.10.2025 by Dr Djian
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Summary
  • UNDERSTANDING THE DURATION OF ACTION OF HYALURONIC ACID
  • DURATION OF ACTION OF HYALURONIC ACID DEPENDING ON THE AREA TREATED
  • FACTORS INFLUENCING THE DURATION OF INJECTIONS
  • HOW TO PROLONG THE EFFECTS OF HYALURONIC ACID?
  • WHAT DURATION REVEALS: AN INDICATOR OF OVERALL QUALITY
  • A MORE ETHICAL APPROACH TO AESTHETICS
  • CONCLUSION: BETWEEN NATURALNESS, DURABILITY AND INTELLIGENT MAINTENANCE
In short
  • The duration of the effects of hyaluronic acid varies between 6 and 24 months according to the treated area shorter on lips or the nasolabial folds, longer on the cheekbones, the chin or the sunken rings.
  • The product works by water retention and stimulation of collagen, but it depends on the type of hyaluronic acid, the cross-linking, the injection depth and metabolism of the patient.
  • The UV, the heat, the tobacco, l’alcohol and a bad hydration accelerate product resorption and reduce the durability of the result.
  • To prolong the effects, it is advisable to hydrate regularly, protect your skin with a SPF 50, to maintain a antioxidant nutrition and associate, if necessary, hyaluronic acid and botox.
  • Lasting results depend on product quality, the precision of the medical gesture and the choice of practitioner. In case of error or excess, the effect can be corrected with hyaluronidase safe.

A tired face, marked wrinkles, a valley of tears, lion wrinkle and then, a few days later, a new hyaluronic acid injection, skin is rejuvenated, cheekbones are lifted, lips are redefined and crow's feet are softened. This medical treatment not only fills creases, it also stimulates collagen production and body hydration by retaining water.
However, despite its volumizing properties and proven efficacy, this absorbable substance is not eternal. Depending on the area injected, the density of the product, lifestyle habits or age, results can last from a few months to almost two years. Understanding what influences this durability not only helps to prolong effects, but also to maintain skin quality over time and slow down skin aging.

 

UNDERSTANDING THE DURATION OF ACTION OF HYALURONIC ACID

 

WHAT IS HYALURONIC ACID AND HOW DOES IT WORK?

 

Hyaluronic acid is often presented as a the ultimate anti-aging molecule. Naturally present in the body, it is an essential component of the connective tissue, which supports and protects the body's other tissues. It is found in skin, the synovial fluid joints and the’glass mood of the eye.

In the skin, it plays a key role in the dermis, where he is responsible for structure maintenance and the cohesion skin layers. Thanks to its properties viscoelastic, hyaluronic acid acts like a biological sponge It captures water, fills intercellular spaces and restores the skin's natural bounced and its freshness.

Every day, a significant portion of this molecule is produced and then degraded naturally. With the aging, production slows down: the skin loses its firmness, dries out and the wrinkles appear. By the age of 50, only about half of the initial amount present during childhood is retained.

To compensate for this loss, the aesthetic medicine has recourse to hyaluronic acid injections. Injected into the dermis, the product restores volumes, stimulates collagen production and improves skin texture. Sound volumizing effect is immediate, while its biological action extends over time.

Biodegradable and perfectly tolerated, hyaluronic acid is today's leading filling product of reference. There are several types of hyaluronic acid used in aesthetic medicine, which have a direct influence on the duration of the result. :

  • Fluid gels are used to moisturize and smooth fine lines,
  • Cross-linked products, are designed for deep filling and restoration of facial volumes.

 

TEMPORARY BUT ADJUSTABLE EFFECTIVENESS

 

Hyaluronic acid is an absorbable product It is naturally degraded by an enzyme called hyaluronidase. This degradation varies according to the area injected, the type of product used, the depth of the procedure and individual metabolism.
On average, the effects last between 6 and 24 months. More superficial injections fade more quickly, while deeper volumes, such as the cheekbones or chin, They keep longer.
The rate of degradation also depends on lifestyle: exposure to the sun, smoking, intense physical activity or an unbalanced diet all accelerate product disappearance. Conversely, good hydration, an appropriate skincare routine and regular medical check-ups help maintain results for longer.

For a personalized evaluation and to find out the optimal duration for your skin, book an appointment at Cabinet du Docteur Djian , aesthetic doctor in Paris, specialist in hyaluronic acid injections.

 

DURATION OF ACTION OF HYALURONIC ACID DEPENDING ON THE AREA TREATED

 

Each area of the face reacts differently according to its exposure to movement, skin thickness and density. These factors determine the speed at which the hyaluronic acid resorbs and the frequency of touch-ups required.

 

duration of hyaluronic acid

 

HIGH-MOBILITY ZONES: SHORTER EFFECTS

 

The most mobile areas, such as lips, the nasolabial folds or the expression lines, The results are more ephemeral. Repeated muscle movements accelerate product degradation. In general The effects last from 6 to 9 months in these areas.
Llip injection with hyaluronic acid is one of the most frequent requests. It restores volume, redefines the lip contour and improves hydration, while maintaining a natural appearance. For the nasolabial folds, filling provides an immediate rejuvenating effect by smoothing out bitterness lines.
Movable areas often require an initial touch-up after 8 to 10 months to maintain the symmetry and flexibility of the result.

 

FIXED ZONES: PROLONGED EFFECTS

 

The cheekbones, the chin or the nose offer far greater durability. These zones, less subject to muscle contraction, retain the effects between 12 and 18 months.
Lhyaluronic acid on the chin can reshape the oval of the face, refine the profile and harmonize volumes without surgery. Similarly, cheekbone injections enhance relief and restore facial structure.
The nose, benefits from the medical rhinoplasty A non-surgical correction in just a few minutes, ideal for softening a profile or straightening a drooping tip. These stable areas are often the ones that retain their desired shape and volume the longest.

 

SPECIAL CASES

 

Some areas, such as the sunken rings or the valleys of tears, offer remarkably long-lasting results, ranging from up to 24 months. The treatment of dark circles requires extreme precision and a perfect knowledge of anatomy, as the skin is thin and mobile.
Other areas, such as the neck or the décolleté require more fluid products, designed to enhance hydration and texture rather than create volume.

The immediate effect observed after the session usually stabilizes after about ten days, the time it takes for the molecule to integrate naturally into the tissue.

Discover before/after photos on the cosmetic surgeon Docteur Djian in Paris to view the actual results for each zone.

 

FACTORS INFLUENCING THE DURATION OF INJECTIONS

 

FACTORS INTERNAL TO THE PATIENT

 

The service life of an injection largely depends on the’patient's body. Individual metabolism, age, skin quality and hydration play an essential role. A healthy skin fine or dehydrated retains the injected substance less well. Conversely, a skin dense and well-moisturized offers greater durability. Smoking, stress, hormonal changes or sun exposure accelerate the product's natural degradation.

The people younger people often benefit from longer-lasting action, Their collagen production is more active. That's why follow-up and maintenance are personalized according to skin type, age and lifestyle.

 

PRODUCT AND TECHNICAL FACTORS

 

The type of product injectedhis cross-linking (gel densification rate) and the depth of gesture have a direct influence on long-term hold. Highly cross-linked hyaluronic acid is denser and resorbs more slowly, making it ideal for restoring the skin's youthful appearance. volume cheekbones or chin.
The more fluid gels, used to smooth superficial wrinkles or moisturize lips, offer a shorter duration but a more natural effect. The injected quantity, the level of precision and the practitioner technique also determine the quality of the final result.
The experience of aesthetic doctor is decisive: a mastered gesture ensures better integration of the product and uniformity of rendering.

 

BAD HABITS THAT REDUCE PERFORMANCE

 

After an injection, certain habits can compromise the durability of the treatment. L’prolonged exposure to heat, the sauna, the UV, the tobacco or the abrasive care accelerate product absorption. A poor hydration or a lack of sleep slow down skin regeneration and alter the filling effect.

Conversely, a a balanced lifestyle, a a diet rich in antioxidants and daily moisturizing care extend the beauty of the result.
Compliance with post-injection advice, in particular the first 48 hours, is essential to guarantee stable, long-lasting results.

 

HOW TO PROLONG THE EFFECTS OF HYALURONIC ACID?

 

how to prolong the AH effect

CARE AND HYGIENE

 

Prolonging the effects of a hyaluronic acid injection depends directly on the care given to the skin after treatment.

  • Drinking water enables the product to attract and retain moisture, a prerequisite for its volumizing effect. Without sufficient moisture, skin slackens more quickly.
  • A a diet rich in antioxidants protects cells from oxidative stress and slows product degradation.
  • The tobacco and the’alcohol, by reducing tissue oxygenation, accelerate its resorption.
  • The sun protection prevents UV rays from destroying collagen and weakening the dermis, maintaining firmness and elasticity for longer.
  • The adapted moisturizers reinforce the skin barrier and preserve tissue cohesion.

 

Well-moisturized, nourished and protected skin retains volume better, which means fewer touch-ups and longer-lasting effects.

 

COMPLEMENTARY CARE

 

Certain combinations enhance the effects of hyaluronic acid injections. The combination with botox injection (botulinum toxin) relaxes facial muscles and prevents the reappearance of expression lines, while preserving natural mobility.
The skin boosters or the gentle peels maintain the skin's luminosity and tone. These aesthetic medicine are complementary, each acting at a specific level of the dermis to improve skin quality.
Finally, techniques such as jawline contouring or the russian lip can also be combined for a global remodeling and harmonious face.

 

OPTIMAL PACE OF TOUCH-UPS

 

The timing of touch-ups therefore depends on the area treated and the type of product injected. For lips or the nasolabial folds, A light touch-up can be performed every 8 to 10 months. More stable areas, such as the chin or cheekbones, rarely require surgery before 18 months.
The important thing is not to wait until all the product has disappeared. Regular, measured touch-ups help preserve a natural result, without excess volume.
Each consultation with the practitioner to adjust the strategy, depending on the evolution of the face and the lifestyle of the patient.

For tailor-made care and lasting results, book an appointment for a hyaluronic acid injection in Paris with the Doctor Djian, a recognized expert in facial reshaping.

 

WHAT DURATION REVEALS: AN INDICATOR OF OVERALL QUALITY

 

A LASTING EFFECT, A SIGN OF GOOD PRODUCT INTEGRATION

 

The reaction of the skin after a hyaluronic acid injection reflects both the quality of injected product and the precision of the medical gesture. When the molecule is deposited at the right depth and blends harmoniously into the tissues, the result is natural, homogeneous and durable. Skin remains supple, volume balanced and texture remains uniform.

Conversely, a incorrect injection - too superficial a product, too much quantity, unsuitable technique or poor anatomical knowledge - can lead to visible irregularities, and balls under the skin, a asymmetry or a accelerated resorption. In some cases, this can lead to localized edema, a bluish discoloration (Tyndall effect) or a poor product positioning.

This is why the choice of practitioner, the type of product used, its concentration and injection depth is decisive.

 

THE IMPORTANCE OF MEDICAL FOLLOW-UP

 

Regular follow-up after each injection is essential to maintain the durability of the result. A aesthetic doctor evaluates the evolution of the skin, the reaction of the injected product and the symmetry of the face. This check-up makes it possible to’adjust volumes and avoid overloading. The Doctor Jérémy Djian offers personalized care for every patient, including recommendations adapted to age, skin type and lifestyle. A planned light touch-up over time, so you don't have to “start from scratch” at every session, and contributes to gradual rejuvenation that respects the face's natural expression.

 

THE PSYCHOLOGICAL DIMENSION OF EPHEMERAL RESULTS

 

The reversibility of hyaluronic acid is often perceived as an advantage. Unlike a surgical procedure such as a face lift, The treatment remains temporary, adjustable and without major risk. This limited duration allows us to adapt to facial evolution, aesthetic tastes and age-related changes.

Knowing that the product disappears naturally over time reassures many patients: they can test a light remodelling, observe the result, then decide whether or not to continue. This flexibility encourages a more serene relationship with aesthetic transformation.

As the Doctor Djian,

The aim is not to freeze the face, but to make it evolve harmoniously..”

 

A MORE ETHICAL APPROACH TO AESTHETICS

 

The quest for naturalness is gradually replacing the quest for transformation. The ideal face is one that retains its expression, movement and uniqueness. Patients are now looking for a balance between skincare, aesthetics and skin health. Hyaluronic acid becomes a tool for preserving skin capital, more than an anti-aging treatment.
The trend in harmonious rejuvenation is essential: correct, yes, but without freezing. And in this process, mastery of time and duration remains the key.

 

CONCLUSION: BETWEEN NATURALNESS, DURABILITY AND INTELLIGENT MAINTENANCE

 

Hyaluronic acid is more than just a dermal filler. It acts as a genuine biological ally, restoring suppleness, volume and radiance to the skin. Its duration of action depends as much on the treated area than type of product injected, the skin quality and lifestyle. On average, results last from 6 to 24 months, but with regular maintenance and a customized approach, the effects can last much longer. Well-executed injections don't alter expressions, they soften them. The key is to choose an experienced practitioner capable of adapting each treatment to individual morphology and needs.

To obtain natural, long-lasting results, take appointment with Doctor Djian in Parisan expert in aesthetic medicine and specialist in hyaluronic acid injections.

Your Questions

FREQUENTLY ASKED QUESTIONS ABOUT HYALURONIC ACID DURATION

HOW LONG WILL IT TAKE TO SEE THE FINAL RESULT?

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The effects of hyaluronic acid are visible immediately after the session, but the final result will be stabilizes after 7 to 10 days. During this time, the substance integrates into the tissues and gradually attracts water, reinforcing hydration and volume. Certain areas, such as dark circles or cheekbones, may require 2 weeks to reveal their final look. The initial slight swelling disappears naturally.

DOES HYALURONIC ACID DISAPPEAR COMPLETELY?

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Yes, hyaluronic acid is a fully absorbable substance.. Over the months, it deteriorates under the action of the hyaluronidase, an enzyme naturally present in the body. The process is gradual and harmless. The face returns to its original appearance, but often with improved skin quality thanks to collagen stimulation. Treated areas retain a certain suppleness and increased hydration, even after the product has completely disappeared.

IS THERE A RISK IN REPEATING INJECTIONS?

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Repeat injections of hyaluronic acid do not present any particular risk when carried out by a trained practitioner. Visit products used are biocompatible and sterile, designed to integrate naturally into the tissues. What counts is precision of gesture, knowledge of anatomy and respect for the intervals between each session. Injections that are too close together or excessive can weigh down the face or create irregularities.
Individual follow-up at Docteur Djian's practice in Paris guarantees a balanced approach, with constant control of skin texture and rendering.

DOES THE EFFECT LAST LESS AFTER SEVERAL SESSIONS?

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On the contrary, results tend to last longer after several sessions. Repeated collagen stimulation and improved skin hydration strengthen the structure of the dermis. Each new injection acts on skin that is already more toned and better prepared to receive the product. As a result, the need for touch-ups is spaced out over time, with a cumulative effect of discreet, long-lasting rejuvenation.

WHEN DOES HYALURONIC ACID DEFLATE?

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After a hyaluronic acid injection, slight swelling may appear in the hours that follow at the various injection points. This is a normal reaction to the injection and water retention. This transient volume generally diminishes between 24 and 72 hours, sometimes up to 5 days depending on the area treated. The final result is stabilized once the oedema has been reabsorbed, when the product integrates harmoniously into the tissues and the skin regains its natural appearance.
To reduce swelling after a hyaluronic acid injection, apply cold locally without pressure, For example, sleep with your head elevated and drink plenty of water to promote drainage. Avoid all massage.

WHEN DO YOU SEE THE EFFECTS OF HYALURONIC ACID?

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The effects of hyaluronic acid are visible immediately after injection, The product instantly fills volumes and smoothes wrinkles. However, the final result appears after a few days, once the slight post-treatment swelling has subsided and the molecule has fully integrated into the tissue. In general between 5 and 10 days to appreciate the natural, even finish. Meanwhile, hyaluronic acid captures water, improves hydration and stimulates the collagen production, offering a gradual, long-lasting effect.

HOW LONG DOES AN INJECTION SESSION LAST?

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A hyaluronic acid injection session lasts an average of 10 to 15 minutes, depending on the number of areas treated and the technique used. After a preliminary consultation, the doctor disinfects the skin, traces the markings and then injects the product with precision. The procedure is fast, painless and involves no social eviction.

HOW TO REVERSE THE EFFECT OF HYALURONIC ACID?

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The effect of a hyaluronic acid injection can be reversed with a hyaluronidase injection, an enzyme capable of dissolve the product immediately. This treatment is used in cases of excess volume, asymmetry or poor gel integration. Performed by a aesthetic doctor, The procedure is fast, safe and reversible.

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Dr. Jérémy Djian
Dr. Jérémy Djian

Dr Jérémy Djian is a plastic surgeon based at 5 square Thiers, near the Victor Hugo roundabout, in the 16th arrondissement of Paris.

He trained in Paris and remains attached to the hospital in the prestigious department of Pr Laurent Lantieri.

 

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